Molecular brakes regulating mTORC1 activation in skeletal muscle following synergist ablation
نویسندگان
چکیده
منابع مشابه
Molecular brakes regulating mTORC1 activation in skeletal muscle following synergist ablation
The goal of the current work was to profile positive (mTORC1 activation, autocrine/paracrine growth factors) and negative [AMPK, unfolded protein response (UPR)] pathways that might regulate overload-induced mTORC1 (mTOR complex 1) activation with the hypothesis that a number of negative regulators of mTORC1 will be engaged during a supraphysiological model of hypertrophy. To achieve this, mTOR...
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ژورنال
عنوان ژورنال: American Journal of Physiology-Endocrinology and Metabolism
سال: 2014
ISSN: 0193-1849,1522-1555
DOI: 10.1152/ajpendo.00674.2013